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October 22, 2020#

pseudohyponatremia in dka

Noncompliance with therapy has also been reported to be a major precipitating cause for DKA in urban black and medically indigent patients. This is because we need to differentiate plasma and plasma water. 48. Tong YJ, Røder ME, Pitchumoni CS. Pseudohyponatremia in Hypertriglyceridemia-Induced Acute Pancreatitis: A Tool for Diagnosis Rather Than Merely a Laboratory Error? 29. When the potassium level is between 3.3 and 5.2 mEq per L, potassium replacement should be initiated.4 Some guidelines recommend potassium replacement with potassium chloride, whereas others recommend combining it with potassium phosphate or potassium acetate. Furthermore, in many cases, the patient or caregiver is unaware of the signs and symptoms of decompensated diabetes, or the patient is unable to treat the progressive dehydration. Because of these potential benefits, careful phosphate replacement may be indicated in patients with cardiac dysfunction, anemia, respiratory depression, and in those with serum phosphate concentration lower than 1.0–1.5 mg/dl. Kim HE. As most stories do, this one begins with a case. 2011;34(4):852–854. Extreme hypercholesterolemia presenting with pseudohyponatremia - a case report and review of the literature. Smiley D, Olanzapine-induced diabetic ketoacidosis. Table 2 provides the differential diagnosis of DKA.14,18, The diagnosis of DKA (Table 3) is based on an elevated serum glucose level (greater than 250 mg per dL [13.88 mmol per L]), an elevated serum ketone level, a pH less than 7.3, and a serum bicarbonate level less than 18 mEq per L (18 mmol per L).4 Although arterial blood gas measurement remains the most widely recommended test for determining pH, measurement of venous blood gas has gained acceptance. 30. Vighnesh Walavalkar, MD Most persons with DKA have type 1 diabetes. Kitabchi AE, Newton M, Once again, nephrology saves the day! Enlarge Wilson DR, 28. Cengiz T. In: Parrillo JE, Dellinger RP, eds. National standards for diabetes self-management education. Emerg Med Australas. Mortality rates are 2–5% for DKA and 15% for HHS, and mortality is usually a consequence of the underlying precipitating cause(s) rather than a result of the metabolic changes of hyperglycemia. Menchine et al evaluated the accuracy of blood gas vs biochemistry testing in Emergency Room patients presenting with diabetic ketoacidosis (DKA). Table 4 provides formulas to calculate the anion gap, serum osmolality, osmolar gap, and serum sodium correction.16 [ Ghetti S, Risperidone-associated transient diabetic ketoacidosis and diabetes mellitus type 1 in a patient treated with valproate and lithium.

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